Small businesses face various federal, state, and local taxes, including income tax, self-employment tax, employment tax, estimated tax, excise tax, and sales tax. They may be eligible for deductions and credits, such as those for business expenses, depreciation, and tax credits like Work Opportunity Tax Credit or Small Business Health Care Tax Credit. Record-keeping, timely estimated tax payments, and awareness of filing deadlines are crucial. Resources like the IRS Small Business and Self-Employed Tax Center, state tax offices, and hiring tax professionals can aid compliance. There's no fixed income threshold for small businesses, and estimated taxes are required if expecting over $1,000 in tax liability. Understanding tax rules and seeking professional help can ease the burden and knowing the ins and outs of tax deductions and credits can make it less costly for small business owners.